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Generic Allegra - Fexofenadine
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CLASS and MECHANISM of Action
Generic Allegra is a medicine for oral administration and it is used to treat the signs and symptoms of allergy that are due to histamine. Histamine is released from histamine-storing cells (mast cells) and then attaches to other cells that have receptors for histamine.
Generic Allegra reduces allergy symptoms of hay fever (seasonal allergic rhinitis), and may reduce itching of the skin in those people with chronic itchy skin rashes. Symptoms treated effectively were sneezing, rhinorrhea, itchy nose/palate/throat, itchy/watery/red eyes.
Active Ingredients: histamine
Inactive Ingredients: cellulose, pregelatinized starch, croscarmellose sodium and magnesium stearate,.
What is Generic Allegra PRESCRIBED For?
Generic Allegra is used to prevent sneezing, runny nose, itching and watering of the eyes, and other allergic symptoms. It may also be used for purposes other than those listed in this medication guide.
How Should I Take Generic Allegra?
Generic Allegra is taken by mouth. Usually it is administrated twice a day, in the morning and the evening. Each dose should be taken with a full glass of water. Do not take this medicine with grapefruit, orange, or apple juice because they may change how well the medicine works. You may take this medicine with food.
Do not take Generic Allegra close to a dose of an antacid that contains aluminum or magnesium such as Rolaids, Maalox, Mylanta, Milk of Magnesia, Pepcid Complete, and others. These antacids may decrease the effects of Generic Allegra. . Follow your doctor's instructions.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. Generic Allegra is usually prescribed for children 6 years of age and older.
Keep out of the reach of children in a container that small children cannot open.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture.
Throw away any unused medicine after the expiration date.
What are the CONTRAINDICATIONS for taking Generic Allegra?
Generic Allegra is contraindicated to persons that ever had an allergic reaction to it or its components. Before taken Generic Allegra you should consult your health care professional if you have any serious illness such as heart, kidney, or liver disease. You may require a dosage adjustment or special monitoring during treatment if you have other illnesses.
Generic Allegra is contraindicated to children younger than 6 years of age.
If you are pregnant or plan to be pregnant talk to your health care professional about all consequences you may have taken this medicine. It is not known if Generic Allegra passes into breast milk. Do not take Generic Allegra without first talking to your health care professional if you are breast-feeding a baby.
What Happens if I MISS A DOSE?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose.
NOTE: Do not take double or extra doses.
What happens if I OVERDOSE?
Seek emergency medical attention. Symptoms of a Generic Allegra overdose include an irregular heartbeat, nausea and vomiting, headache, drowsiness, sweating, increased thirst, weakness, and restlessness.
What are the possible SIDE EFFECTS of Generic Allegra?
Besides all the benefits Generic Allegra has, some side effects were also noticed. It is not obligatory to have any of the side effects listed below. However, if some of them occur seek medical attention immediately.
IN RARE INSTANCES you may have:
The above side effects usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your health care professional if any of the following side effects continue or are bothersome.
- chest tightness;
- feeling of warmth;
- redness of the face, neck, arms and occasionally, upper chest;
- large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs;
- shortness of breath, difficult or labored breathing
LESS COMMON side effects are:
If any of the above side effects occur inform your health care professional immediately
- Back pain;
- body aches or pain;
- difficulty in moving;
- ear congestion;
- joint pain;
- loss of voice ;
- muscle aching or cramping;
- muscle pains or stiffness;
- nasal congestion;
- pain in arms or legs;
- pain or tenderness around eyes or cheekbones;
- painful menstrual bleeding;
- ringing or buzzing in ears;
- runny or stuffy nose;
- sore throat;
- stomach upset;
- swollen joints;
- unusual feeling of tiredness or weakness;
- viral infection (such as cold and flu).
What other drugs can INTERACT with Generic Allegra?
Tell your health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
Generic Allegra can interact with the following medicines:
- grapefruit, apple, or orange juice]
- St. John's Wort
In addition, there are other medicines that can make you feel drowsy:
- medicines for mental problems, anxieties and psychotic disturbances;
- barbiturate medicines for inducing sleep or treating seizures (convulsions);
Fruit juices such as grapefruit, orange and apple may reduce the bioavailability and exposure of fexofenadine. This is based on the results from 3 clinical studies using histamine induced skin wheals and flares coupled with population pharmacokinetic analysis. The size of wheal and flare were significantly larger when fexofenadine was administered with either grapefruit or orange juices compared to water.
Based on the literature reports, the same effects may be extrapolated to other fruit juices such as apple juice. The clinical significance of these observations is unknown.
In addition, based on the population pharmacokinetics analysis of the combined data from grapefruit and orange juices studies with the data from a bioequivalence study, the bioavailability of fexofenadine was reduced by 36%. Therefore, to maximize the effects of fexofenadine, it is recommended that ALLEGRA should be taken with water.