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Generic Nexium - Esomeprazole
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CLASS and MECHANISM of Action
Generic "Nexium" is a proton pump inhibitor which reduces gastric acid secretion through inhibition of H+/K+-ATPase in gastric parietal cells. By inhibiting the functioning of this enzyme, the drug prevents formation of gastric acid. Generic "Nexium" inhibits gastric (stomach) acid secretion. It is used to treat symptoms of heartburn and other symptoms of Gastroesophageal Reflux Disease (GERD). Generic "Nexium" relieves heartburn symptoms by inhibiting the secretion of acid produced in the stomach (gastric acid). Some gastric acid is necessary to digest food, but an excess can cause heartburn and can damage the esophagus. Generic "Nexium" reduces the amount of acid produced in the stomach so that the esophagus can begin to heal.
Active ingredient: Eomeprazole magnesium
Other Ingredients: gelatin, FD&C Blue #1, FD&C Red #40, D&C Red #28, titanium dioxide,
shellac, ethyl alcohol, isopropyl alcohol, n-butyl alcohol, propylene glycol, sodium hydroxide, polyvinyl pyrrolidone, and D&C Yellow #10.
What is Generic "Nexium" PRESCRIBED for?
Generic "Nexium" is designed to be used for short-term treatment (4 to 8 weeks) to heal the damage to the esophagus and to reduce heartburn symptoms that go along with it. For some patients who have not healed after 4 weeks, another 4-8 weeks may be prescribed. Generic "Nexium" is also prescribed for maintenance so patients don't have symptoms of heartburn and so that the esophagus can stay healthy. Use of Generic "Nexium" is not recommended for longer than 6 months.
How should I take Generic "Nexium"?
It is recommended to take each Generic "Nexium" dosage with a full glass of water. Generic "Nexium" should be taken at least one hour before a meal. Do not break or chew the Generic "Nexium" capsules since they are formulated to release slowly in the body. There are no restrictions on food, beverages, or activities while taking Generic "Nexium". Recommended adult Generic "Nexium" dosage for treatment of esophagitis is Generic "Nexium" 20 mg or Generic "Nexium" 40 mg one capsule daily 4 to 8 weeks (unless otherwise directed by your doctor).
Generic "Nexium" should be stored at room temperature between 59 and 86 degrees F (15 and 30 degrees C) in a tightly-closed container, away from heat, light, and moisture. Do not store Generic "Nexium" in the bathroom.
What are the CONTRADICTIONS for taking Generic "Nexium"?
You should not take Generic "Nexium"if you are allergic to esomeprazole, lansoprazole, omeprazole, pantoprazole or rabeprazole.
Before taking Generic "Nexium" tell your doctor if you have ever had any type of liver disease. You may not be able to take Generic "Nexium", or you may require a dosage adjustment or special monitoring.
Do not take Generic "Nexium" without first talking to your doctor if you are pregnant or could become pregnant during treatment.
Generic "Nexium"is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby.
Do not take Generic "Nexium"without first talking to your doctor if you are breast-feeding a baby. It is not known whether Generic "Nexium"passes into breast milk.
What Happens if I MISS A DOSE?
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.
What Happens if I OVERDOSE?
In case of overdose, call emergency or your local poison control center. Symptoms of an Generic "Nexium" overdose include reduced motor activity, difficulty breathing, tremor, uncoordinated movements, and convulsions.
What are the possible SIDE EFFECTS of Generic "Nexium"
If you experience an allergic reaction
stop taking Generic "Nexium" and seek emergency medical attention.
- difficulty breathing
- closing of your throat
- swelling of your lips, tongue, or face; or hives
Other, less serious side effects may be more likely to occur. Continue to take Generic "Nexium" and talk to your doctor if you experience
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
- nausea, flatulence, abdominal pain, or constipation; or
- dry mouth.
What other drugs can INTERACT with Generic "Nexium"?
Before taking Generic "Nexium", tell your doctor if you are taking any of the following medicines:
You may not be able to take Generic "Nexium", or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.
- digoxin (Lanoxin, Lanoxicaps);
- itraconazole (Sporanox) or ketoconazole (Nizoral); or
- iron (Feosol, Mol-Iron, Fergon, Femiron, others).
Since most drugs have side effects in the long run, if your symptoms were not serious and you feel better, it may be a good idea to stop the Generic "Nexium" if your doctor thinks your condition is fully treated. Sometimes doctors put patients on medicines and do not reevaluate often enough whether the patient still needs the medicines. Your pharmacist has additional information about Generic "Nexium" written for health professionals that you may read. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.